Review of Ophthalmology Archive December 2011 : Page 2

AS YOUR PATIENT’S DAY CHANGES, SO WILL THEIR IOP. In your offi ce, you only see a snapshot of their IOP. Keep IOP controlled throughout the day, choose TRAVATAN Z ® Solution. Complete the 2-step process in managing IOP with BAK-free TRAVATAN Z ® Solution 1 LOWER IOP BY 30% 1 2 SUSTAIN IT UP TO A FULL DAY 1,2 Eyelash Changes: Gradual change to eyelashes including increased length, thickness and number of lashes. Usually reversible. ADVERSE REACTIONS: Most common adverse reaction (30% to 50%) is conjunctival hyperemia. USE IN SPECIFIC POPULATIONS: Use in pediatric patients below the age of 16 years is not recommended because of potential safety concerns related to increased pigmentation following long-term chronic use. INDICATIONS AND USAGE: TRAVATAN Z ® Solution is a prostaglandin analog indicated for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension. DOSAGE AND ADMINISTRATION: One drop in the affected eye(s) once daily in the evening. IMPORTANT SAFETY INFORMATION: WARNINGS AND PRECAUTIONS: Pigmentation: Pigmentation of the iris, periorbital tissue (eyelid) and eyelashes can occur. Iris pigmentation likely to be permanent. References: 1. Lewis RA, Katz GJ, Weiss MJ, et al. Travoprost 0.004% with and without benzalkonium chloride: a comparison of safety and effi cacy. J Glaucoma . 2007;16(1):98-103. 2. Gross RL, Peace JH, Smith SE, et al. Duration of IOP reduction with travoprost BAK-free solution. J Glaucoma . 2008;17(3):217-222. Before prescribing TRAVATAN Z ® Ophthalmic Solution, please read the brief summary of prescribing information. Lower it. Sustain it. © 2011 Novartis 8/11 TRV11503JAD

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