Review of Ophthalmology April 2012 : Page 3
Re-engineered. Re-designed. t  5SFBUTUIFTJHOTBOETZNQUPNTBTTPDJBUFE with acute blepharitis 1,2 t  %FMJWFSTFRVJWBMFOUMFWFMTPGEFYBNFUIBTPOF to the anterior chamber with one-half of the DPODFOUSBUJPO �f;�a;SFMBUJWFUP50#3"%&9 ® (tobramycin/dexamethasone ophthalmic suspension) 0.3%/0.1% 1,2 In those diseases causing thinning of the cornea or sclera, perforations have been known to occur with the use of topical steroids. The initial prescription and renewal of the medication order should be made by a physician only after examination of the patient with the aid of magnifi cation such as slit lamp biomicroscopy and, where appropriate, fl uorescein staining t  #BDUFSJBMJOGFDUJPOTQSPMPOHFEVTFPG corticosteroids may suppress the host response and thus increase the hazard of secondary ocular infections. In acute purulent conditions, steroids may mask infection or enhance existing infection. If signs and symptoms fail to improve after 2 days, the patient should be re-evaluated t  7JSBMJOGFDUJPOTFNQMPZNFOUPGB corticosteroid medication in the treatment of patients with a history of herpes simplex requires great caution. Use of ocular steroids may prolong the course and may exacerbate the severity of many viral infections of the eye (including herpes simplex) t  'VOHBMJOGFDUJPOTGVOHBMJOGFDUJPOTPGUIF cornea are particularly prone to develop coincidentally with long-term local steroid application. Fungus invasion must be considered in any persistent corneal ulceration where a steroid has been used or is in use t  *GQSPEVDUJTVTFEJODPNCJOBUJPOXJUITZTUFNJD aminoglycoside antibiotics the patient should be monitored for total serum concentration of tobramycin Please see prescribing information on adjacent page.